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Drug Discovery, Drug Delivery, and Biochemical Assays
ProFoldin’s products and services are employed by universities, research institutes, biotech
companies, pharmaceutical R&D and research hospitals worldwide in life sciences and drug discovery.
Liposomal Zinc

Liposomal zinc is designed for delivery of zinc across the cell membranes.   Zinc chloride at an internal concentration of 2 mM is encapsulated in the liposome. The external zinc concentration is 0.2 mM.  To ensure the delivery efficiency, the lipid composition of the liposomal zinc is the same as that for a liposomal drug in clinic which is HSPC: DSPE-PEG2000: cholesterol (3:1:1, mass ratio). The average size of liposomes is about 110 nm.

The PEGylated Liposomal Zinc (Catalog No. PHPC002ZN) includes 2 ml of 2 mM ZnCl2 encapsulated in 7 mg/ml PEGylated liposomes. The external solution is 0.1 M NaCl.