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Drug Discovery, Drug Delivery, and Biochemical Assays
ProFoldin’s products and services are employed by universities, research institutes, biotech
companies, pharmaceutical R&D and research hospitals worldwide in life sciences and drug discovery.

Enzymes and Substrates

We offer various drug target enzymes and substrates. Please click the product link for price information or place an order online. You may also contact us for a quote. We offer discount rates for bulk orders.

Human enzymes 



DNA topoisomerases


DNA polymerases


Poly (ADP-ribose) polymerase

RNA polymerase


Viral enzymes

RNA polymerase


Enzyme substrates and templates for polymerases


  • Supercoiled DNA for DNA relaxation assays (Catalog No.SDNA-050UG)
  • Relaxed DNA for DNA supercoiling assays (Catalog No.RDNA-050UG)
  • Concatenated DNA for DNA relaxation assays (Catalog No.KDNA-100)
  • Nicked DNA for DNA ligase assay (Catalog No.NLA100K-DNA)
  • DNA template for human DNA polymerase alpha assay (Catalog No.HDPA100K-DNA)
  • DNA template for human DNA polymerase beta assay (Catalog No.DPB100K-DNA)
  • DNA template for human DNA polymerase gamma assay (Catalog No.DPG100K-DNA)
  • DNA template for mitochondrial RNA polymerase assay (Catalog No.MRPA100K-DNA)
  • DNA template for E. coli RNA polymerase assay (Catalog No.RPA100K-DNA)
  • DNA template for S. aureus RNA polymerase assay (Catalog No.RPA100KS-DNA)
  • DNA template for bacteriophage T7 RNA polymerase assay (Catalog No.T7RPA100K-DNA)
  • DNA template for M-MLV reverse transcriptase assay (Catalog No.MLV100K-DNA)
  • DNA template for HIV reverse transcriptase assay (Catalog No.HIV100K-DNA)
  • DNA template for AMV reverse transcriptase assay (Catalog No.AMV100K-DNA)
  • RNA template for viral RNA-dependent RNA polymerase assay (Catalog No.VRT100K-RNA)
  • RNA template for E. coli polynucleotide phosphorylase assay (Catalog No.PNP100K-RNA)
  • DNA template for E. coli DNA primase assay (Catalog No.EGA100K-DNA)
  • DNA template for H. influenza DNA primase assay (Catalog No.HGA100K-DNA)
  • DNA template for S. pneumonia DNA primase assay (Catalog No.PGA100K-DNA)
  • DNA template for S. aureus DNA primase assay (Catalog No.AGA100K-DNA)
  • MurC substrate - UDP-MurNAc (Catalog No.MURC-SUB1)
  • MurD substrate - UDP-MurNAc-L-Ala (Catalog No.MURD-SUB1)
  • MurE substarte - UDP-MurNAc-dipeptide (Catalog No.MURE-SUB1)
  • MurF substarte - UDP-MurNAc-tripeptide (Catalog No.MURF-SUB1)



Bacterial enzymes and proteins


DNA gyrases

DNA helicase

DNA ligase

DNA polymerase

DNA primase

DNA topoisomerase I

DNA topoisomerase II 

See DNA gyrase 


DNA topoisomerase IV (the parC-parE complex)

DNA-binding protein


Methylerythritol phosphate cytidyltransferase (IspD)






PncB (Nicotinate phosphoribosyltransferase)

RNA polymerase

UDP-N-acetylglucosamine pyrophosphorylase (GlmU)