Liposomal Ciprofloxacin

The PEGylated and non-PEGylated liposomal ciprofloxacin contains 1 mg/ml ciprofloxacin.  The PEGylated liposome is composed of  hydrogenated soy phosphocholine (HSPC), 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG2000) and cholesterol at a mass ratio of  HSPC:DSPE:Cholesterol of 3:1:1.  The Non-PEGylated liposome is composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and cholesterol at a mass ratio of DPPC:cheleterol of 1.9:1.  The ciprofloxacin encapsulation percentage is more than 95 %. The average size of liposomes is about 80 nm with poly dispersity index (dpi) of 0.1.

The DPPC Liposomal Ciprofloxacin- 2 mg (Catalog No. DPPC002CP) contains 2 ml of liposomal ciprofloxacin at concentrations of 1 mg/ml ciprofloxacin and 23 mg/ml of lipids composed of HSPC and cholesterol.

The PEGylated HSPC Liposomal Ciprofloxacin- 2 mg (Catalog No. PHPC002CP) contains 2 ml of liposomal ciprofloxacin at concentrations of 1 mg/ml ciprofloxacin and 18 mg/ml of lipids composed of DSPE-PEG2000, HSPC and cholesterol.