Guanylate Kinase Assays
Guanylate kinase is essential for recycling GMP and cGMP. It catalyzes the ATP-dependent phosphorylation of GMP into GDP. Guanylate kinase is an attractive antibacterial target. The guanylate
GMP + ATP = GDP + ADP
kinase assay is based on measurement of ADP generated from the kinase reaction. The assay is fluorescence-based and can be carried out using regular black 96-well or 384-well plates or cuvettes.
E. coli Guanylate Kinase Assay Kit Plus (Catalog number: GMK100KE)
E. coli Guanylate Kinase Assay Kit Plus-500 (Catalog number: GMK500KE)
S. pneumoniae Guanylate kinase Assay Kit Plus-500 (GMK500KN)