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Drug Discovery, Drug Delivery, and Biochemical Assays
ProFoldin’s products and services are employed by universities, research institutes, biotech
companies, pharmaceutical R&D and research hospitals worldwide in life sciences and drug discovery.
Carfilzomib Assay

Carfilzomib is an anti-cancer drug. It is a peptide derivative that selectively inhibits the activity of the 20S proteasome. The MicroGram Carfilzomib Assay Kit is designed for measurement of micrograms of carfilzomib.  The assay is based on increase of fluorescence at 535 nm of the assay reagent C33 in the presence of carfilzomib.  The assay kit can be used for measurement of carfilzomib concentrations in drug discovery and development.

Due to the insolubility of carfilzomib in water, measurement of carfilzomib concentration is performed in ethanol. The assay is not compatible with thiol compounds or metal chelators such EDTA.

The MicroGram Carfilzomib Assay Kit (Catalog number CFZ200) includes 1 ml of 10 x C33 dye for 200 assays using 96-well plates.  Cuvettes may also be used for the assay.