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Drug Discovery, Drug Delivery, and Biochemical Assays
ProFoldin’s products and services are employed by universities, research institutes, biotech
companies, pharmaceutical R&D and research hospitals worldwide in life sciences and drug discovery.
Gel-Based Human Topoisomerase I DNA relaxation Assay

Human DNA topoisomerase I (topo I) converts supercoiled circular DNA into relaxed DNA (DNA relaxation reaction).  The Gel-Based Human Topoisomerase I DNA relaxation Assay Kit is based on the principle that the supercoiled DNA and relaxed DNA are separated by agarose gel electrophoresis.  Fluorescence-based DNA relaxation assays in a 96-well pate format are also available for high throughput screening of human topo I inhibitors.   

 

Gel-Based Human Topoisomerase I DNA relaxation Assay Kit (Catalog No. GHRA100KE)