The DNA-binding plates are coated with cations that interact with nucleic acids which are anions. Since the binding is based on charge-charge interactions, the plates may also be used for RNA binding. If the bound DNA is a single-strand DNA, the bound DNA can specifically recognize its complementary strand by G-C and A-T base pairing. Therefore, the 96-well DNA-binding plates can be potentially used for studies of nucleic acid – nucleic acid interactions or nucleic acid – protein interactions. The transparent background of the plate provides an option of detection of the bound molecules based on light absorbance.
The unit price is for a pack of 4 plates.
Please notice: If the plates are used to study nucleic acid – nucleic acid interaction, it is recommended to block the non-specific interactions with the Nucleic Acid Binding Blocker (Catalog number NBP96N) after the first nucleic acid has bound to the plate.