ProFoldin provides innovative protein preparation and assay technologies for drug discovery and academic research, specifically in the following areas:

 

Protein preparation and stability

Protein folding columns                           Protein folding solutions

Membrane protein extraction kits              Membrane protein folding kits

DNA removal kit                                     Protein stability and aggregation assay

Desalting columns

 

Protein drug target activity assays

ATPases                                              Kinases                            

DNA primases                                        DNA ligases    

RNA polymerases                                   DNA polymerase III a           

DNA polymerase b                                  Human PARP-1

DNA topoisomerase I (relaxation)              DNA topoisomerase II (supercoiling)

DNA topoisomerase IV (decatenation)       Topoisomerase DNA cleavage  

            Proteases                                                         ß-lactamases 

 

Molecular concentration assays

Protein concentrations                            DNA concentrations

ADP, GDP, UDP, CDP concentrations             Phosphate concentrations

Amino acid concentrations                       Coenzyme A (CoA) concentrations 

Detergent concentrations                              Detergent CMC determination                   

Phosphatidylcholine concentrations                     Polyphosphate concentrations

Zinc concentrations                                            Copper concentrations

Nicole / Cobalt concentrations                             Chloride, bromide and iodide concentrations

 

Binding assays

Protein - protein interactions

Protein – DNA interactions

DNA – DNA interactions