Enzymes, substrates and templates

 

We offer various drug target enzymes and substrates.  Please click the product link for price information or place an order online. You may also contact us for a quote. We offer discount rates for bulk orders.

You may email your PO or the completed Order Form to info@profoldin.com, or fax it to 508-845-9258. Thanks.

Human enzymes
DNA topoisomerase    
  Human DNA topoisomerase I - for 2500 assays Catalog No. HTOPI-010
  Human DNA topoisomerase I - for 10,000 assays Catalog No. HTOPI-040
DNA polymerase    
  Human DNA polymerase alpha - for 100 assays Catalog No. HDPA1-100
  Human DNA polymerase alpha - for 1000 assays Catalog No. HDPA1-1000
  Human DNA polymerase alpha holoenzyme - for 100 assays Catalog No. HDPA-100
  Human DNA polymerase beta - for 100 assays Catalog No. HDPB-100
  Human DNA polymerase beta - for 1000 assays Catalog No. HDPB-1000
Kinase    
  Human thymidylate kinase (TMK) - for 500 assays Catalog No. HTMK-500
Poly (ADP-ribose) Polymerase-1  (PARP-1)    
  Human Poly (ADP-ribose) Polymerase-1 - for 100 assays Catalog No. PARP-100
  Human Poly (ADP-ribose) Polymerase-1 - for 1000 assays Catalog No. PARP-1000
RNA polymerase    
  Human mitochondrial RNA polymerase - for 100 assays Catalog No. MRPA-100
       
Bacterial enzymes and proteins
Beta-Lactamase    
  E. coli beta-lactamase - for 100 assays Catalog No. LAC-100EC
Biotin protein ligase (BirA)    
  E. coli BirA - for 100 assays Catalog No. BIRA-100KEC
D-Ala-D-Ala ligase    
  E. coli D-Ala-D-Ala ligase - for 100 assays Catalog No. DDL-100EC
DNA gyrase (bacterial DNA topoisomerase II)    
  E. coli DNA gyrase - for 100 assays Catalog No. TOP2-100EC
  E. coli gyrA - for 100 assays Catalog No. GYRA-100EC
  E. coli gyrB - for 100 assays Catalog No. GYRB-100EC
  S. aureus DNA gyrase - for 100 assays Catalog No. TOP2-100SA
  S. aureus gyrA - for 100 assays Catalog No. GYRA-100SA
  S. aureus gyrB - for 100 assays Catalog No. GYRB-100SA
  P. aeruginosa DNA gyrase - for 100 assays Catalog No. TOP2-100PA
  P. aeruginosa gyrA - for 100 assays Catalog No. GYRA-100PA
  P. aeruginosa gyrB - for 100 assays Catalog No. GYRB-100PA
DNA helicase    
  E. coli DNA helicase - for 100 assays Catalog No. DNAB-100EC
  H. influenza DNA helicase - for 100 assays Catalog No. DNAB-100HI
  P. aeruginosa DNA helicase - for 100 assays Catalog No. DNAB-100PA
  S. pneumonia DNA helicase - for 100 assays Catalog No. DNAB-100SP
DNA ligase    
  E. coli DNA ligase - for 100 assays Catalog No. LIG-100EC
DNA polymerase    
  E. coli DNA polymerase alpha - for 100 assays Catalog No. DPA-100EC
  S. pneumonia DNA polymerase alpha - for 100 assays Catalog No. DPA-100SP
  H. influenza DNA polymerase alpha - for 100 assays Catalog No. DPA-100HI
DNA primase    
  E. coli DNA primase - for 100 assays Catalog No. DNAG-100EC
  H. influenza DNA primase - for 100 assays Catalog No. DNAG-100HI
  S. pneumonia DNA primase - for 100 assays Catalog No. DNAG-100SP
  S. aureus DNA primase - for 100 assays Catalog No. DNAG-100SA
DNA topoisomerase I     
  E. coli DNA topoisomerase I - for 100 assays Catalog No. TOP1-100EC
DNA topoisomerase II    
  see DNA gyrase    
DNA topoisomerase IV (the parC-parE complex)    
  E. coli DNA topoisomerase IV - for 100 assays Catalog No. TOP4-100EC
  E. coli parC - for 100 assays Catalog No. PARC-100EC
  E. coli parE - for 100 assays Catalog No. PARE-100EC
  S. aureus DNA topoisomerase IV - for 100 assays Catalog No. TOP4-100SA
  S. aureus parC - for 100 assays Catalog No. PARC-100SA
  S. aureus parE - for 100 assays Catalog No. PARE-100SA
  P. aeruginosa DNA topoisomerase IV - for 100 assays Catalog No. TOP4-100PA
  P. aeruginosa parC - for 100 assays Catalog No. PARC-100PA
  P. aeruginosa parE - for 100 assays Catalog No. PARE-100PA
  S. pneumoniae DNA topoisomerase IV - for 100 assays Catalog No. TOP4-100SP
  S. pneumoniae parC - for 100 assays Catalog No. PARC-100SP
  S. pneumoniae parE - for 100 assays Catalog No. PARE-100SP
DNA-binding protein    
  E. coli single-strand DNA binding protein - 100 µg Catalog No. SSB-100EC
kinase    
  E. coli NAD kinase - for 100 assays Catalog No. NADK-100EC
  E. coli thymidylate kinase (TMK) - for 100 assays Catalog No. TMK-100EC
  E. coli UMP kinase - for 100 assays Catalog No. UMK-100EC
  E. coli guanylate kinase - for 100 assays Catalog No. GMK-10EC
  S. pneumoniae guanylate kinase - for 100 assays Catalog No. GMK-100SP
Methylerythritol phosphate cytidyltransferase (IspD)    
  E. coli IspD - for 100 assays Catalog No. ISPD-100EC
  P. aeruginosa IspD - for 100 assays Catalog No. ISPD-100PA
MurA    
  E. coli MurA - for 100 assays Catalog No. MURA-100EC
MurC    
  E. coli MurC - for 100 assays Catalog No. MURC-100EC
  P. aeruginosa MurC - for 100 assays Catalog No. MURC-100PA
  S. pneumonia MurC - for 100 assays Catalog No. MURC-100SP
MurD    
  E. coli MurD - for 100 assays Catalog No. MURD-100EC
  P. aeruginosa MurD - for 100 assays Catalog No. MURD-100PA
  S. aureus MurD - for 100 assays Catalog No. MURD-100SA
MurE    
  E. coli MurE - for 100 assays Catalog No. MURE-100EC
       
MurF    
  E. coli MurF - for 100 assays Catalog No. MURF-100EC
  P. aeruginosa MurF - for 100 assays Catalog No. MURF-100PA
  S. aureus MurF - for 100 assays Catalog No. MURF-100SA
  S. pneumonia MurF - for 100 assays Catalog No. MURF-100SP
Nicotinate phosphoribosyltransferase (PncB)    
  S. aureus PncB - for 100 assays Catalog No. PNCB-100SA
S. pneumonia PncB - for 100 assays Catalog No. PNCB-100SP
RNA polymerase    
  E. coli RNA polymerase - for 100 assays Catalog No. RNAP-100EC
  S. aureus RNA polymerase - for 100 assays Catalog No. RNAP-100SA
  E. coli polynucleotide phosphorylase - for 100 assays Catalog No. PNP-100EC
UDP-N-acetylglucosamine pyrophosphorylase (GlmU)    
  E. coli GlmU - for 100 assays Catalog No. GLMU-100EC
       
Enzyme substrates and templates for polymerases
  Supercoiled DNA for DNA relaxation assays Catalog No. SDNA-050UG
  Relaxed DNA for DNA supercoiling assays Catalog No. RDNA-050UG
  Concatenated DNA for DNA relaxation assays Catalog No. KDNA-100
  Nicked DNA for DNA ligase assay Catalog No. NLA100K-DNA
  DNA template for human DNA polymerase alpha assay Catalog No. HDPA100K-DNA
  DNA template for human DNA polymerase beta assay Catalog No. DPB100K-DNA
  DNA template for human DNA polymerase gamma assay Catalog No. DPG100K-DNA
  DNA template for mitochondrial RNA polymerase assay Catalog No. MRPA100K-DNA
  DNA template for E. coli RNA polymerase assay Catalog No. RPA100K-DNA
  DNA template for S. aureus RNA polymerase assay Catalog No. RPA100KS-DNA
  DNA template for bacteriophage T7 RNA polymerase assay  Catalog No. T7RPA100K-DNA
  DNA template for M-MLV reverse transcriptase assay Catalog No. MLV100K-DNA
  DNA template for HIV reverse transcriptase assay Catalog No. HIV100K-DNA
  DNA template for AMV reverse transcriptase assay Catalog No. AMV100K-DNA
  RNA template for viral RNA-dependent RNA polymerase assay Catalog No. VRT100K-RNA
  RNA template for E. coli polynucleotide phosphorylase assay Catalog No. PNP100K-RNA
  DNA template for E. coli DNA primase assay Catalog No. EGA100K-DNA
  DNA template for H. influenza DNA primase assay Catalog No. HGA100K-DNA
  DNA template for S. pneumonia DNA primase assay Catalog No. PGA100K-DNA
  DNA template for S. aureus DNA primase assay Catalog No. AGA100K-DNA
  MurC substrate - UDP-MurNAc Catalog No. MURC-SUB1
  MurD substrate - UDP-MurNAc-L-Ala Catalog No. MURD-SUB1
  MurE substarte - UDP-MurNAc-dipeptide Catalog No. MURE-SUB1
  MurF substarte - UDP-MurNAc-tripeptide Catalog No. MURF-SUB1