Liposomal drug formulations provide great opportunities of improving the drug efficacy and toxicity profiles.  Drug molecules with amine groups such as doxorubicin and ciprofloxacin, etc. can be loaded by ammonium-based pH gradient.  The Ready-to-load DPPC Liposomes with Ammonium Tartrate (Catalog number DPC100AT) are high quality non-PEGylated liposomes that are ready to load drug molecules containing amine groups. The drug loading process is completed in about 3 hours after mixing the drug with the liposomes. The composition of the liposomes is DPPC and cholesterol in the weight ratio of 1.9:1. The total lipid concentration is 20 mg/ml. The liposomes are encapsulated with ammonium tartrate for drug remote loading.  The average size of liposomes is about 80 nm with poly dispersity index (dpi) of 0.1.

The Ready-to-load DPPC Liposomes with Ammonium Tartrate (Catalog number DPC100AT) includes 10 ml liposomes with 10 mg/ml lipid concentration. The mass ratio of lipids is DPPC: cholesterol = 1.9:1. The concentration of ammonium tartrate encapsulated within the liposomes for drug loading is 300 mM. The buffer is 10 mM histidine, pH 6.5, 9.2 % sucrose. Liposomes are stored in a 2°C to 8°C refrigerator.   DO NOT freeze liposomes.